Four Republican senators have expressed reservations about their party’s plan to repeal Obamacare, throwing the health bill’s fate into uncertainty.

Ted Cruz, Ron Johnson, Mike Lee and Rand Paul said they were “not ready to vote for this bill”, but were “open to negotiation”.

The Senate’s Republican leader unveiled his plan to overhaul the US healthcare system after drafting it in secret.

The party can only afford to have two defections to pass the measure.

According to BBC News, Republicans need to secure 50 votes when the bill comes to the floor next week. No Democrats are expected to support it.

Forty-three people were arrested yesterday while protesting against the legislation outside the office of Senate Majority Leader Mitch McConnell, who crafted most of the plan.

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